Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Key Documents

363A-1

Sigma-Aldrich

PAX-8 Rabbit Polyclonal Antibody

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (363A-14)
vial of 0.5 mL concentrate (363A-15)
bottle of 1.0 mL predilute (363A-17)
bottle of 7.0 mL predilute (363A-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry: 1:25-1:100

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... PAX8(7849)

General description

PAX-8 is a transcription factor expressed during the embryonic development of Müllerian organs,kidneys, and thyroid, with continued expression in some epithelial cell types of these maturetissues. PAX-8 is a useful marker for neoplasms of gynecologic, renal, and thyroidorigin. This antibody targets the N-terminus of the PAX-8 molecule. This section of the protein isshared with other PAX proteins such as PAX-5 and PAX-6; thus, some cross-reactivitywith these proteins may be observed as evidenced by the labeling of selected lymphocytes, andneuroendocrine cells.

Quality


IVD
IVD
IVD
RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Biljana Pauzar et al.
Collegium antropologicum, 36 Suppl 2, 79-82 (2013-02-13)
US-guided fine needle aspiration cytology is currently the best diagnostic tool for thyroid nodules. However, it is not sensitive and specific enough for differentiating between benign and malignant follicular tumors. A potentially useful marker for this differentiation is the PAX8-PPARgamma
Control of sheath back bleeding: a simplified approach.
G I Gabliani et al.
Catheterization and cardiovascular diagnosis, 13(6), 427-427 (1987-11-01)
Ping Zhang et al.
Pathology international, 56(5), 240-245 (2006-05-04)
Thyroid transcription factor 1 (TTF1), thyroid transcription factor 2 (TTF2) and paired box gene 8 (Pax8) are demonstrated to play a crucial role for the differentiation and organogenesis of thyroid follicular cells. Their roles in thyroid carcinogenesis are not very
Daisuke Nonaka et al.
The American journal of surgical pathology, 32(10), 1566-1571 (2008-08-30)
The ovary is a common site of involvement for metastasis and the breast is one of the most common sources. Metastatic breast carcinoma can mimic a primary ovarian carcinoma. Pax8 is a crucial transcription factor for organogenesis of the thyroid
Daisuke Nonaka et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21(2), 192-200 (2007-12-18)
Thyroid-specific transcription factors, Pax8, TTF-1, and TTF-2, are crucial for thyroid organogenesis and differentiation. Compared with TTF-1, the other two markers have scarcely been investigated in surgical pathology. The goal of this study is to evaluate the expressions of these
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico