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Key Documents

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Y0001611

Esculetin

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

6,7-Dihydroxycoumarin, Cichorigenin, Esculetin

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About This Item

Fórmula empírica (notación de Hill):
C9H6O4
Número de CAS:
305-01-1
Peso molecular:
178.14
Beilstein/REAXYS Number:
152788
MDL number:
MFCD00006874
UNSPSC Code:
41116107
PubChem Substance ID:
329831510
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

esculetin

manufacturer/tradename

EDQM

mp

271-273 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Oc1cc2OC(=O)C=Cc2cc1O

InChI

1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H

InChI key

ILEDWLMCKZNDJK-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Esculetin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Molecular cancer, 15(1), 64-64 (2016-10-21)
A handful of studies have exploited antitumor potential of esculetin, a dihydroxy coumarine derivative; the targets to which it binds and the possible downstream mechanism for its cytotoxicity in cancer cells remain to be elucidated. Using pancreatic cancer cell lines
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Journal of toxicology and environmental health. Part A, 78(2), 109-118 (2014-11-27)
Coumarins are naturally occurring compounds, widely distributed throughout the plant kingdom (Plantae), and possess important pharmacological properties, including inhibition of oxidative stress. In this context, newly synthesized coumarin compounds are being produced due to their potent antioxidant activities. Therefore, the
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Plant science : an international journal of experimental plant biology, 234, 60-73 (2015-03-26)
Glycosyltransferases play diverse roles in cellular metabolism by modifying the activities of regulatory metabolites. Three stress-regulated UDP-glucosyltransferase-encoding genes have been isolated from the stigmas of saffron, UGT85U1, UGT85U2 and UGT85V1, which belong to the UGT85 family that includes members associated

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