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P5504

Sigma-Aldrich

Potassium phosphate dibasic trihydrate

ReagentPlus®, ≥99.0%

Sinónimos:

Dipotassium hydrogen phosphate trihydrate, Dipotassium phosphate, di-Potassium hydrogen phosphate trihydrate

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About This Item

Fórmula lineal:
K2HPO4 · 3H2O
Número de CAS:
16788-57-1
Peso molecular:
228.22
EC Number:
231-834-5
MDL number:
MFCD00149926
UNSPSC Code:
12161700
PubChem Substance ID:
57654537
NACRES:
NA.25

Quality Level

200

product line

ReagentPlus®

assay

≥99.0%

form

powder or crystals

pH

9.2-9.4 (25 °C, 50 g/L)

solubility

water: 100 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

O.O.O.[K+].[K+].OP([O-])([O-])=O

InChI

1S/2K.H3O4P.3H2O/c;;1-5(2,3)4;;;/h;;(H3,1,2,3,4);3*1H2/q2*+1;;;;/p-2

InChI key

XQGPKZUNMMFTAL-UHFFFAOYSA-L

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General description

Potassium phosphate solution have very high buffering capacity that is widely used in molecular biology, biochemistry, and chromatography. Potassium phosphate dibasic trihydrate is a key component of potassium phosphate buffer, phosphate-buffered saline (PBS), and phosphate-buffered EDTA (PBE). It is extensively used in the preparation of biological samples for various biological experiments. Potassium phosphate buffer is also used in methods such as equilibrium dialysis, high-performance liquid chromatography (HPLC), and affinity capillary electrophoresis (ACE) to study the characteristics of drug-protein interactions in the body. Potassium phosphate buffer solutions consist of mixtures of the potassium phosphate monobasic and potassium phosphate dibasic forms.

Application

Potassium phosphate dibasic trihydrate has been used in the preparation of potassium phosphate buffer for the resuspension of polyelectrolyte capsules. It has also been used as a buffer during glutaminase‑1 (GLS-1) enzyme assay and GLS-2 enzyme assay.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
SLCL6227
SLCM0037
SLCM0865
SLCK3843
SLCK4050

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Plants live in close relationships with complex populations of microorganisms, including rhizobacterial species commonly referred to as plant growth-promoting rhizobacteria (PGPR). PGPR are able to improve plant productivity, but the molecular mechanisms involved in this process remain largely unknown. Using
Michael J Soth et al.
Journal of medicinal chemistry, 63(21), 12957-12977 (2020-10-30)
Inhibition of glutaminase-1 (GLS-1) hampers the proliferation of tumor cells reliant on glutamine. Known glutaminase inhibitors have potential limitations, and in vivo exposures are potentially limited due to poor physicochemical properties. We initiated a GLS-1 inhibitor discovery program focused on
Ala A A Al-Subeihi et al.
Toxicology and applied pharmacology, 283(2), 117-126 (2015-01-01)
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