05670
Allantoin
≥98.0% (N)
Sinónimos:
NSC 7606, 5-Ureidohydantoin, Glyoxylic(acid) diureide
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About This Item
Fórmula empírica (notación de Hill):
C4H6N4O3
Número de CAS:
Peso molecular:
158.12
Beilstein/REAXYS Number:
102364
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
≥98.0% (N)
form
powder
ign. residue
≤0.2%
mp
230 °C (dec.) (lit.)
functional group
amine
SMILES string
NC(=O)NC1NC(=O)NC1=O
InChI
1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)
InChI key
POJWUDADGALRAB-UHFFFAOYSA-N
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Categorías relacionadas
Application
Reactant for:
Synthesis of Mannich bases for use as antibacterial agents
Synthesis of sulofenur analogs for use as antitumor agents
Synthesis of Mannich bases for use as antibacterial agents
Synthesis of sulofenur analogs for use as antitumor agents
Biochem/physiol Actions
Purine metabolite via the uric acid pathway. Uric acid also reacts with free radicals to produce allantoin, thus allantoin may be a useful biomarker for oxidative stress.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Los clientes también vieron
Sh. Joshi
Oxidation Communications, 32, 714-723 (2009)
Khairia M. Youssef, et al
Medicinal Chemistry Research, 11, 481-503 (2003)
Rufus Turner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 891-892, 85-89 (2012-03-09)
Allantoin is the major oxidation product of urate in humans and is a potential biomarker of oxidative stress. Several methods are used to measure allantoin in biological samples but they have inherent issues that can include lack of specificity and
Dora Il'yasova et al.
Clinica chimica acta; international journal of clinical chemistry, 413(19-20), 1446-1453 (2012-06-12)
Oxidative damage produced by reactive oxygen species (ROS) has been implicated in the etiology and pathology of many health conditions, including a large number of chronic diseases. Urinary biomarkers of oxidative status present a great opportunity to study redox balance
Camila G Moreira et al.
Journal of ethnopharmacology, 141(3), 1005-1011 (2012-04-17)
Pyrostegia venusta is a native Brazilian plant which has a variety of uses in traditional folk medicine including the treatment of vitiligo. However, its effectiveness on melanogenesis is not yet elucidated. This study aimed to investigate the melanogenic activity of
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