ALD00578

2-Bromopyridin-3-yl sulfurofluoridate

95%

• Fórmula empírica (notación de Hill): C₅H₃BrFNO₃S
• Peso molecular: 256.05
• UNSPSC Code: 12352200
• PubChem Substance ID: 329772722
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 95%
• form: liquid
• refractive index: n20/D 1.5160
• transition temp: flash point >230 °F
• density: 1.8283 g/mL
• storage temp.: 2-8°C

Descripción

Application

2-Bromopyridin-3-yl sulfurofluoridate can be used in the Pd-catalyzed Suzuki-Miyuara cross-coupling reaction. The fluorosulfate functionality was shown by Sharpless and coworkers to have distinct reactivity in comparison to other functional groups used in Suzuki-Miyuara reactions, such as bromides, chlorides and triflates. This inherent property provides a strong potential for selective Suzuki-Miyuara couplings for chemoselective reaction sequences.

Other Notes

Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates

Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates

Información de seguridad

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3