748854

Iodotrimethylsilane solution

1 M in dichloromethane

• Sinónimos: Iodotrimethylsilane solution, TMS iodine, TMS-I, TMSI, Trimethyliodosilane
• Fórmula empírica (notación de Hill): C₃H₉ISi
• Peso molecular: 200.09
• UNSPSC Code: 12352101
• NACRES: NA.22

Propiedades

• form: liquid
• concentration: 1 M in dichloromethane
• refractive index: n20/D 1.433
• density: 1.334 g/mL at 25 °C
• storage temp.: 2-8°C

Descripción

General description

Iodotrimethylsilane [(CH₃)₃SiI] is an important and versatile organosilicon reagent with wide applications in organic synthesis. It is used as a neutral nucleophilic reagent, trimethylsilylating agent, Lewis acid catalyst, reducing agent and dehydrating agent in many organic reactions.

Application

Iodotrimethylsilane can be used as:

• A reagent in the hydroiodation of ynamides to yield the important building blocks (E)-α-iodoenamides.
• A reagent in the synthesis of (1-iodovinyl) arenes by hydroiodation of trimethylsilyl ethynylarenes.

Información de seguridad

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H314,H336,H351
• pcodes: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH014
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -23.8 °F
• flash_point_c: -31 °C