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The anti-inflammatory vasostatin-2 attenuates atherosclerosis in ApoE

Thrombosis and haemostasis (2016-11-11)
Weixin Xiong, Xiaoqun Wang, Daopeng Dai, Bao Zhang, Lin Lu, Rong Tao
ABSTRACT

We showed previously that reduced level of vasostatin-2 (VS-2) correlates to the presence and severity of coronary artery disease. In this study, we aimed to figure out the role of chromogranin A (CGA) derived VS-2 in the development of atherosclerosis and monocyte/macrophage recruitment. Apolipoprotein E-deficient (ApoE