- [Inductive effects of enzymes of salicylic acid derivatives].
[Inductive effects of enzymes of salicylic acid derivatives].
Comptes rendus des seances de la Societe de biologie et de ses filiales (1982-01-01)
H Goudonnet, J Mounié, K Bereksi-Reguig, R Truchot
PMID6220776
ABSTRACT
In the series of salicylic acids derivatives investigated 3,5-DIS has a large inductive effect of enzymes with respect to the metabolism of xenobiotics: rise in the rate of Cyt. P 450; increase of ethoxycoumarin deethylase, bilirubin glucuronosyl transferase and benzphetamine-N-demethylase activities. This effect is comparable with that of phenobarbital.
MATERIALS