- Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4-acetylsulphamethoxazole in the snail Cepaea hortensis.
Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4-acetylsulphamethoxazole in the snail Cepaea hortensis.
The Veterinary quarterly (1987-10-01)
T B Vree, M L Vree, J F Nouws
PMID3424644
ABSTRACT
The snail Cepaea hortensis is able to acetylate and hydroxylate sulphamethoxazole in a similar way to man. About one percent deacetylation, but no hydroxylation of N4-acetysulphamethoxazole takes place. The relative rates of the metabolic pathways for hydroxylation and acetylation of sulphamethoxazole are equal.
MATERIALS
Product Number
Brand
Product Description
Sulfamethoxazole impurity A, European Pharmacopoeia (EP) Reference Standard