- A new antiinflammatory agent (EGIS-5645) without gastrointestinal side-effect.
A new antiinflammatory agent (EGIS-5645) without gastrointestinal side-effect.
Agents and actions. Supplements (1991-01-01)
G Gigler, E Kiszelly, P Tömpe, G Kovács, K Gadó
PMID1906236
ABSTRACT
The compound EGIS-5645 is a potent antipyretic agent possessing analgesic and antiinflammatory properties. The drug is active in antiinflammatory models such as carrageenin oedema and adjuvant arthritis. EGIS-5645 shows practically no gastro-ulcerogenic effect. The molecule does not inhibit either prostaglandin biosynthesis or soybean lipoxygenase enzyme activity.
MATERIALS