MilliporeSigma

Implication of conjugated linoleic acid (CLA) in human health.

Critical reviews in food science and nutrition (2012-03-29)
Allison Dilzer, Yeonhwa Park
ABSTRACT

Conjugated linoleic acid (CLA) has drawn significant attention in the last two decades for its variety of biologically beneficial effects. CLA reduces body fat, cardiovascular diseases and cancer, and modulates immune and inflammatory responses as well as improves bone mass. It has been suggested that the overall effects of CLA are the results of interactions between two major isomers, cis-9,trans-11 and trans-10,cis-12. This review will primarily focus on current CLA publications involving humans, which are also summarized in the tables. Along with a number of beneficial effects of CLA, there are safety considerations for CLA supplementation in humans, which include effects on liver functions, milk fat depression, glucose metabolism, and oxidative stresses.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Linoleic acid sodium salt, ≥98% (GC)
Sigma-Aldrich
Linoleic acid, ≥99%