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  • The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development.

The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development.

Proceedings of the National Academy of Sciences of the United States of America (2011-05-04)
Nils Elfving, Céline Davoine, Reyes Benlloch, Jeanette Blomberg, Kristoffer Brännström, Dörte Müller, Anders Nilsson, Mikael Ulfstedt, Hans Ronne, Gunnar Wingsle, Ove Nilsson, Stefan Björklund
ABSTRACT

Development in plants is controlled by abiotic environmental cues such as day length, light quality, temperature, drought, and salinity. These signals are sensed by a variety of systems and transmitted by different signal transduction pathways. Ultimately, these pathways are integrated to control expression of specific target genes, which encode proteins that regulate development and differentiation. The molecular mechanisms for such integration have remained elusive. We here show that a linear 130-amino-acids-long sequence in the Med25 subunit of the Arabidopsis thaliana Mediator is a common target for the drought response element binding protein 2A, zinc finger homeodomain 1, and Myb-like transcription factors which are involved in different stress response pathways. In addition, our results show that Med25 together with drought response element binding protein 2A also function in repression of PhyB-mediated light signaling and thus integrate signals from different regulatory pathways.

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Hygromycin B from Streptomyces hygroscopicus, powder, BioReagent, suitable for cell culture, suitable for insect cell culture