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Reverse Phase/Normal Phase Chromatography Resins

PharmPrep® silica sorbent used in purification of peptides and small proteins.

Our silica gel chromatography sorbents and gels offer a wide range of choices depending on your separation requirements: whether you need excellent reproducibility and optimal resolution, or a more economic and versatile material, our normal-phase and reverse-phase products include silica gel products for all manufacturing scales.

Reversed phase chromatography sorbents

PharmPrep® P RP sorbent is used for efficient polishing of small peptides like insulin and other APIs, including antibiotics and hormones. These sorbents are also available in prepacked stainless-steel columns.
LiChroprep® RP sorbents provide fast, effective, reproducible separation of peptide purification processes.

Normal-phase chromatography sorbents

Our PharmPrep® P Si and LiChroprep® Si products are well-suited for cost-effective, reliable polishing of biopharmaceutical and pharmaceutical APIs.

Standardized silica gels

Our standardized silica gels are widely used to purify high-value compounds in ton quantities. These silica gels are produced for adsorption and chromatography processes and are available in multiple particle sizes, and pack sizes from 500 g to 400 kg.

Silica Gel 60 is an irregularly shaped silica gel matrix ideal for simple adsorption processes and normal-phase chromatography.

Multifunctional sorbents

Aluminum oxide, available with pore diameters of 6 mm, 9 mm, and 15 mm, is a versatile sorbent for preparative chromatography. Aluminum oxide exhibits higher pH-stability than silica gel, especially in the alkaline range.

Standardized Aluminum Oxide 90 is a sorbent of medium polarity and is frequently used when the cation exchange properties of basic alumina are required. It may be used as an alternative to activated carbon.

Florisil® silicate is a polar, highly selective magnesium silicate gel, well-suited for separation of steroids, alkaloids, and antibiotics.

Related Product Resources

Product Selection

Guide: Biochromatography Portfolio Guide
Guide: Chromatography Product Selection Guide

Product Specifications

Datasheet: PharmPrep® P Sorbent
Datasheet: LiChroprep® Sorbent

Product Operations

Webinar: High-throughput Process Development: Utilizing the Full Potential of Miniature Chromatography Columns
Webinar: Preparative HPLC Part I: How to Build an Efficient Purification Process
Webinar: Preparative HPLC Part II: Process Development and Troubleshooting – A "How to" Guide

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Ion Exchange Chromatography Resins
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Affinity chromatography is often used during the capture phase to isolate the target molecule and reduce process volume. Our range of affinity resins includes Protein A, anti-A and anti-B, and metal chelate resin, designed for high throughput and cost-effective purification.
Buffers & pH Adjusters
Our broad portfolio of buffer materials manufactured according to GMP guidelines includes excipients specifically for drug formulation and manufacturing, including high-risk applications. Whether your product is a small or large molecule drug, we offer high-quality buffers and pH adjusters with regulatory support.
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Highlights

Webinar: How Continuous Chromatography Increases Productivity
Webinar: How Continuous Chromatography Increases Productivity

Increase your productivity 4-20x through applying the principle of continuous chromatography.

Webinar: Overall Process Development for Insulin Purification - from Capturing to Filtration
Webinar: Overall Process Development for Insulin Purification - from Capturing to Filtration

How to complete a combined & optimized method for complete downstream processing of recombinant human insulin & select the most suitable phase combinations.

Webinar: Combined pH/Salt Gradients for the Separation of Challenging Protein Variants
Webinar: Combined pH/Salt Gradients for the Separation of Challenging Protein Variants

How to apply the theory of Linear Gradient Elution, define the best separation conditions with dual gradients, and transfer to a large-scale process.

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