445R-1

NKX2.2 (EP336) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP336, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (445R-14); vial of 0.1 mL concentrate Research Use Only (445R-14-RUO); vial of 0.5 mL concentrate (445R-15); vial of 1.0 mL concentrate (445R-16); vial of 1.0 mL concentrate Research Use Only (445R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (445R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (445R-17); vial of 7.0 mL pre-dilute ready-to-use (445R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (445R-18-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)
• isotype: IgG
• control: Ewing’s sarcoma, pancreas
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear

Description

General description

NKX2.2 is a homeodomain transcription factor that plays a role in neuroendocrine and glial differentiation. NKX2.2 is upregulated in Ewing′s sarcoma as a result of the oncogenic EWS-FLI1 fusion protein. As one of many small round blue cell tumors, Ewing′s sarcoma can be difficult to diagnose due to the characteristic undifferentiated morphology. NKX2.2 has proven its utility as a sensitive maker for distinguishing Ewing′s sarcoma from other round blue cell tumors when used in a panel.

Quality

IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable