OTUB1
OTU domain, ubiquitin aldehyde binding 1
Synonyms:
OTB1, OTU1
Species:
Human OTUB1 (55611), Mouse Otub1 (107260), Rat Otub1 (293705), chicken OTUB1 (777320), domestic cat OTUB1 (101096843), cow OTUB1 (540984), dog OTUB1 (611228), domestic guinea pig Otub1 (100714472), naked mole-rat Otub1 (101706271), sheep OTUB1 (101122063)
UniProtKB ID:
Gene ID:
- Human(55611) Summary: The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- Mouse(107260) OTU domain, ubiquitin aldehyde binding 1
- Rat(293705) OTU domain, ubiquitin aldehyde binding 1
- chicken(777320) OTU domain, ubiquitin aldehyde binding 1
- domestic cat(101096843) OTU domain, ubiquitin aldehyde binding 1
- cow(540984) OTU domain, ubiquitin aldehyde binding 1
- dog(611228) OTU domain, ubiquitin aldehyde binding 1
- domestic guinea pig(100714472) OTU domain, ubiquitin aldehyde binding 1
- naked mole-rat(101706271) OTU domain, ubiquitin aldehyde binding 1
- sheep(101122063) OTU domain, ubiquitin aldehyde binding 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OTUB1 (57-70) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-OTUB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-OTUB1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
western blot
western blot