APP
amyloid beta (A4) precursor protein
Synonyms:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Species:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), domestic cat APP (101085564), cow APP (280722), dog APP (403407), naked mole-rat App (101724743), domestic guinea pig App (100715302)
UniProtKB ID:
Gene ID:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
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Custom Gene Products
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ELISA
Product Number
Description
Species
High Sensitivity Human Amyloid β42 ELISA, This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
Species
human
High Sensitivity Human Amyloid β40 ELISA, This High Sensitivity Human Amyloid β40 ELISA is used to measure & quantify Amyloid β40 levels in Neuroscience research.,
Species
human
Human Amyloid β42 Brain ELISA, This Human Amyloid β42 Brain ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-APP-T668 antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
western blot
Anti- APP antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Biotin Conj. | MAB348B, clone 22C11, from mouse, biotin conjugate,
Species Reactivity
canine, human, monkey, mouse, pig, porcine, rat
Application
immunocytochemistry
immunohistochemistry
immunohistochemistry
Anti-APP Antibody, clone 1D1, clone 1D1, from rat,
Species Reactivity
human
Application
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-Amyloid Antibody, β 37-42, aβ, serum, Chemicon®,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Proteins
Product Number
Description
Species