Ngai Group – Professor Product Portal

Professor Ming-Yu Ngai

Ngai Lab focuses on the development of novel reagents and radical strategies to access open-shell reactive species for the formation of carbon-carbon and carbon-heteroatom bonds. Redox-active di- and trifluoromethoxylating reagents have been developed for direct conversion of (hetero)aryl C-H group into C-OCF₂H and C-OCF₃ groups. The mild reaction conditions tolerate a wide range of functional groups and enable late-stage functionalization of drug-like molecules..

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