The Krische group has developed a broad class of “C-C bond forming transfer hydrogenations” wherein the exchange of hydrogen between alcohols and unsaturated reactants serves to generate aldehyde-organometal pairs that combine to give products of carbonyl addition. This methodology enables direct alcohol CH-functionalization, avoiding discrete alcohol-to-aldehyde redox manipulations. The indicated cyclometallated iridium C,O-benzoate complexes can be handled on the bench top and deployed in aqueous organic media.
Krische Group Website
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