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重要文件

1604803

USP

利托那韦

United States Pharmacopeia (USP) Reference Standard

同義詞:

1,3-噻唑-5-基甲基 N-[(2S,3S,5S)-3-羟基-5-[[(2S)-3-甲基-2-[[甲基-[(2-丙-2-基-1,3-噻唑-4-基)甲基]氨基甲酰基]氨基]丁酰基]氨基]-1,6-二苯基己基-2-基]氨基甲酸酯

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About This Item

經驗公式(希爾表示法):
C37H48N6O5S2
CAS號碼:
分子量::
720.94
分類程式碼代碼:
41116107
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

USP

蒸汽壓力

<0.0000001 kPa ( 25 °C)

API 家族

ritonavir

形狀

powder

包裝

pkg of 200 mg

製造商/商標名

USP

儲存條件

protect from light

顏色

white to tan

溶解度

acetonitrile: slightly soluble
ethanol: freely soluble
methanol: freely soluble
methylene chloride: freely soluble
water: practically insoluble

應用

pharmaceutical (small molecule)

形式

neat

InChI

1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

InChI 密鑰

NCDNCNXCDXHOMX-XGKFQTDJSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

應用

Ritonavir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ritonavir Capsules
  • Ritonavir Tablets
  • Ritonavir Oral Solution
  • Lopinavir and Ritonavir Tablets
  • Lopinavir and Ritonavir Oral Solution

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Ritonavir
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 37(4), 3912-3912 (2020)
Lopinavir and Ritonavir Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 2670-2670 (2013)
Ritonavir Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 3920-3920 (2013)
Lopinavir and Ritonavir Oral Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 2666-2666 (2015)
RP-HPLC method development and validation for simultaneous estimation of Lopinavir and Ritonavir in tablet dosage form
Bindu MJ, et al.
International Journal of Science and Engineering Applications, 5(1), 77-77 (2017)

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