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重要文件

1138201

USP

氯碘羟喹

United States Pharmacopeia (USP) Reference Standard

同義詞:

5-氯-7-碘-8-羟基喹啉, 5-氯-8-羟基-7-碘喹啉, 氯碘喹啉, 氯碘羟喹

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About This Item

經驗公式(希爾表示法):
C9H5ClINO
CAS號碼:
分子量::
305.50
Beilstein:
153637
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

clioquinol

製造商/商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

Oc1c(I)cc(Cl)c2cccnc12

InChI

1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

InChI 密鑰

QCDFBFJGMNKBDO-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Clioquinol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Clioquinol and Hydrocortisone Cream
  • Clioquinol and Hydrocortisone Ointment
  • Clioquinol Cream
  • Clioquinol Ointment
  • Compound Clioquinol Topical Powder

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Kazuyuki Kawamura et al.
Biochemical and biophysical research communications, 452(1), 181-185 (2014-04-24)
Subacute myelo-optico-neuropathy (SMON) is a progressive neurological disorder affecting the spinal cord, peripheral nerves and optic nerves. Although it has been assumed that SMON was caused by intoxication of clioquinol, the mechanism underlying clioquinol-induced neurotoxicity is not fully understood. This
Pei-Teh Chang et al.
Neuropharmacology, 92, 146-157 (2015-01-18)
Alzheimer's disease is a neurodegenerative disorder characterized by deposition of β-amyloid (Aβ) fibrils accompanied with progressive neurite loss. None of the clinically approved anti-Alzheimer's agents target both pathological processes. We hypothesized that conjugation of a metal chelator to destabilize Aβ
Turan Yildiz et al.
International journal of surgery (London, England), 15, 17-22 (2015-02-02)
The aim of this study is to investigate the expected adhesion-modifying effect of clinoquinol which has metal-chelating feature that limits the inflammation and fibroblastic activity. A total of 40 Wistar Albino rats were included, which were divided into 5 groups.

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