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About This Item
經驗公式(希爾表示法):
C10H6N2O2
CAS號碼:
分子量::
186.17
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
生物源
synthetic (organic)
品質等級
化驗
≥98%
形狀
powder
效力
35 μM IC50
溶解度
DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow
儲存溫度
2-8°C
SMILES 字串
Oc1ccc(cc1O)\C=C(\C#N)C#N
InChI
1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
InChI 密鑰
VTJXFTPMFYAJJU-UHFFFAOYSA-N
基因資訊
human ... CDK2(1017)
應用
Tyrphostin 23可作为酪氨酸激酶抑制剂用于研究大鼠ghrelin诱导的GH3细胞MAPK激活。Tyrphostin 23也被用作分析其对神经磷酸酶(SN)诱导的中性粒细胞趋化的作用。
生化/生理作用
Tyrphostin 23是表皮生长因子(EGF)受体激酶功能的小分子抑制剂。该分子与蛋白酪氨酸激酶(PTK)结构域的底物亚位点结合。
特點和優勢
这种化合物是激酶磷酸酶生物学研究的特色产品。点击此处发现更多特色激酶磷酸酶生物产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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