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SRP6472

Sigma-Aldrich

Transferrin human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

同義詞:

DKFZp781D0156, PRO1557, PRO2086, TF

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in HEK 293 cells

籤條

6-His tagged (C-terminus)

化驗

≥95% (SDS-PAGE)

形狀

lyophilized

分子量

calculated mol wt 76 kDa
observed mol wt 74 kDa by SDS-PAGE (DTT-reduced.)

包裝

pkg of 100 μg
pkg of 20 μg

雜質

<1 EU/μg endotoxin (LAL test)

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... TF(7018)

相關類別

一般說明

Transferrin is encoded by the TF gene that is mapped to human chromosome 3q22.1. It is a glycoprotein containing homologous iron-binding domains at N-terminal and C-terminal ends. Transferrin has a molecular weight of 80,000 Da and belongs to the transferrin superfamily, the members of which include lactoferrin, melanotransferrin, and ovotransferrin.

應用

To supplement neurosphere culture medium and sphere differentiation medium.

生化/生理作用

Transferrin is an iron-binding glycoprotein that primarily functions in the transport of plasma iron in vertebrates. It may also have a secondary function of facilitating cell proliferation. The binding of ferric iron to transferrin requires the presence of an anion, that functions as a bridge between the metal and the protein.

外觀

Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.0. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重構

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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Surgical management of atheroma of the aortic dome and origin of supra-aortic trunks.
Thevenet A
World Journal of Surgery, 3, 187-195 (1979)
Genome-wide association study identifies genetic loci associated with iron deficiency.
McLaren CE
PLoS ONE, 6 (2011)
The physiology of transferrin and transferrin receptors.
Huebers HA and Finch CA
Physiological Reviews, 67, 520-582 (1987)
Phylogenetic analyses uncover a novel clade of transferrin in nonmammalian vertebrates.
Mohd-Padil H
Molecular Biology and Evolution, 30, 894-905 (2013)
Iron transport and storage proteins.
P Aisen et al.
Annual review of biochemistry, 49, 357-393 (1980-01-01)

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