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Merck
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重要文件

T1283

Sigma-Aldrich

全转铁蛋白 牛

Iron-saturated, BioReagent, suitable for cell culture

同義詞:

嗜铁蛋白, 嗜铁蛋白,铁饱和

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About This Item

CAS號碼:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.75

品質等級

產品線

BioReagent

化驗

97-100% (agarose gel electrophoresis)

形狀

powder

濃度

~25 mM

技術

cell culture | mammalian: suitable

雜質

endotoxin, tested

溶解度

H2O: 50 mg/mL

UniProt登錄號

運輸包裝

ambient

儲存溫度

2-8°C

基因資訊

bovine ... TF(280705)

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應用

转铁蛋白是一种存在于血清中的主要铁结合和细胞传递分子。 无血清细胞培养系统需要一种铁的传递形式。 转铁蛋白是铁的优选传递形式,因为细胞可通过细胞表面上的转铁蛋白受体以生理学上适当的方式对转铁蛋白结合的铁进行处理。 牛全转铁蛋白可与多种细胞类型一起使用。 牛全转铁蛋白在使用前会加载铁并可被直接添加到贫铁或无铁的细胞培养基中。

分析報告

经琼脂糖凝胶电泳纯度。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Han Hu et al.
Animal science journal = Nihon chikusan Gakkaiho, 87(1), 84-91 (2015-10-16)
In this study, bovine mammary epithelial cells were used to study stress responses after cells were exposed to 42°C for 0.5, 1, 3, 5, 8 or 12 h, and 38°C as control. The transcription of the genes (HSP27, HSP70 and
William Schachterle et al.
Nature communications, 8, 13963-13963 (2017-01-17)
Transplanting vascular endothelial cells (ECs) to support metabolism and express regenerative paracrine factors is a strategy to treat vasculopathies and to promote tissue regeneration. However, transplantation strategies have been challenging to develop, because ECs are difficult to culture and little
Wenting Dai et al.
The British journal of nutrition, 123(5), 489-498 (2019-11-13)
Despite the well-characterised mechanisms of amino acids (AA) regulation of milk protein synthesis in mammary glands (MG), the underlying specific AA regulatory machinery in bovine MG remains further elucidated. As methionine (Met) is one of the most important essential and
Guihua Du et al.
Development (Cambridge, England), 147(8) (2020-03-20)
Continual spermatogenesis relies on the actions of an undifferentiated spermatogonial population that is composed of stem cells and progenitors. Here, using mouse models, we explored the role of RNA-binding proteins (RBPs) in regulation of the biological activities of this population.
Francis Biville et al.
PloS one, 9(10), e107612-e107612 (2014-10-08)
The ability to acquire iron from various sources has been demonstrated to be a major determinant in the pathogenesis of Neisseria meningitidis. Outside the cells, iron is bound to transferrin in serum, or to lactoferrin in mucosal secretions. Meningococci can

文章

转铁蛋白和其他细胞培养成分如何影响无血清、无蛋白细胞培养系统(用于生物制造包括单克隆抗体在内的异源蛋白)的性能。本页介绍转铁蛋白的体外化学和生物化学。

How transferrin and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of transferrin.

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