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Merck
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重要文件

SML3811

Sigma-Aldrich

Hygromycin A

≥98% (HPLC)

同義詞:

Totomycin, 5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-D-neo-inositol, Homomycin, Hygromycin

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About This Item

經驗公式(希爾表示法):
C23H29NO12
CAS號碼:
分子量::
511.48
分類程式碼代碼:
51111800
分類程式碼代碼:
12352200
NACRES:
NA.21

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

-10 to -25°C

SMILES 字串

O[C@H]1[C@]2([H])[C@@]([C@@H]([C@@H]([C@@H]1O)NC(/C(C)=C/C3=CC=C(C(O)=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]4O)O)C(C)=O)=O)O)([H])OCO2

InChI

1S/C23H29NO12/c1-8(22(32)24-13-14(27)16(29)21-20(15(13)28)33-7-34-21)5-10-3-4-12(11(26)6-10)35-23-18(31)17(30)19(36-23)9(2)25/h3-6,13-21,23,26-31H,7H2,1-2H3,(H,24,32)/b8-5+/t13-,14+,15-,16-,17+,18+,19-,20+,21-,23-/m1/s1

InChI 密鑰

YQYJSBFKSSDGFO-IIHALWDASA-N

生化/生理作用

An orally available antibiotic; selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi
Hygromycin A is an orally available antibiotic produced by Streptomyces hygroscopicus that targets the ribosomal 23S rRNA. Hygromycin A is selectively taken up by nucleoside transporter specific to spirochete bacteria including Borreliella burgdorferi, which causes Lyme disease. It clears B. burgdorferi infection in mice with lesser disruption of micron=biome than clinical antibiotics.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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