SML3585

PSB-CB5

≥98% (HPLC)

• 同義詞: 5H-Imidazo[2,1-b][1,3]thiazin-3(2H)-one, 2-[[3-[(4-chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-, (2Z)
• 經驗公式（希爾表示法）: C₂₀H₁₇ClN₂O₂S
• CAS號碼: 1627710-30-8
• 分子量：: 384.88
• 分類程式碼代碼: 51111800
• 分類程式碼代碼: 12352200
• NACRES: NA.21

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear (Warmed)
• 儲存溫度: 2-8°C
• SMILES 字串: O=C1N2C(SCCC2)=N/C1=C\C3=CC(OCC4=CC=C(C=C4)Cl)=CC=C3
• InChI 密鑰: XJBQRMOGMULGPP-PDGQHHTCSA-N

描述

生化／生理作用

PSB-CB5 is a potent and selective GPR18 antagonist that inhibits Δ9-THC-induced GPR18 β-arrestin recruitment (IC50 = 279 nM; [THC] = EC50 = 7.5 μM) with no potency against human GPR55 (IC50 >10 μM) and little or no affinity toward human CB2 and CB1 (Ki = 4.03 μM & >10 μM, respectively).

Potent and selective GPR18 antagonist with little or no potency towrd human GPR55, CB1 or CB2.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable