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Merck
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重要文件

SML1394

Sigma-Aldrich

奥美沙坦

≥98% (HPLC)

同義詞:

4-(1-羟基-1-甲基乙基)-2-丙基-1- [ [2′--(2H-四唑-5-基) [1,1′--联苯 ]-4-基 ] 甲基 ]-1H-咪唑-5-羧酸, 奥美沙坦酸

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About This Item

經驗公式(希爾表示法):
C24H26N6O3
CAS號碼:
分子量::
446.50
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 20 mg/mL, clear

儲存溫度

2-8°C

SMILES 字串

OC(C)(C)C1=C(C(O)=O)N(CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2)C(CCC)=N1

InChI

1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)

InChI 密鑰

VTRAEEWXHOVJFV-UHFFFAOYSA-N

基因資訊

human ... AGTR1(185)

應用

奥美沙坦已用作血管紧张素 II 受体 1(AT1) 的受体抑制剂,用于研究血管紧张素 II 1 型受体相互作用在调节血管紧张素 II 依赖性高血压中肾传入小动脉的作用。

生化/生理作用

奥美沙坦具有抗炎和抗氧化应激特性。它保护神经元细胞免于低聚淀粉样蛋白β(Aβ)诱导的细胞衰老。
奥美沙坦是一种血管紧张素 ⅡⅠ 型受体阻滞剂。
奥美沙坦是一种血管紧张素 ⅡⅠ 型受体阻滞剂。奥美沙坦是降压药奥美沙坦酯的活性形式。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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