SML3317

Losartan

≥98% (HPLC), powder, angiotensin II receptor type 1 (AT1) antagonist

• 同義詞: 1-[1-[[2′-(2H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1H-imidazol-5-yl]methanol, 2-Butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-1H-imidazole-5-methanol, 2-Butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, DUP 89
• 經驗公式（希爾表示法）: C₂₂H₂₃ClN₆O
• CAS號碼: 114798-26-4
• 分子量：: 422.91
• MDL號碼: MFCD19686114
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• product name: Losartan, ≥98% (HPLC)
• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2
• InChI: 1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)
• InChI 密鑰: PSIFNNKUMBGKDQ-UHFFFAOYSA-N

描述

生化／生理作用

Losartan is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan is used for treatment of hypertension.

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H317,H360FD,H362
• 防範說明: P202 - P260 - P263 - P280 - P302 + P352 - P308 + P313
• 危險分類: Lact. - Repr. 1B - Skin Sens. 1
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable