SML0757

WS6

≥98% (HPLC)

• 同義詞: 4-[[6-[(Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzeneacetamide, WS-6
• 經驗公式（希爾表示法）: C₂₉H₃₁F₃N₆O₃
• CAS號碼: 1421227-53-3
• 分子量：: 568.59
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• InChI: 1S/C29H31F3N6O3/c1-37-10-12-38(13-11-37)17-21-6-7-22(15-24(21)29(30,31)32)35-26(39)14-19-2-8-23(9-3-19)41-27-16-25(33-18-34-27)36-28(40)20-4-5-20/h2-3,6-9,15-16,18,20H,4-5,10-14,17H2,1H3,(H,35,39)(H,33,34,36,40)
• InChI 密鑰: FTODTDQFHDJWIQ-UHFFFAOYSA-N

描述

生化／生理作用

WS6 is an inducer of β cell proliferation, thought to act primarily through modulating the activities of the IKB kinase pathway and ErbB3-binding protein 1 (EBP1) also known as proliferation-associated protein 2G4 (PA2G4), an RNA-binding protein that is involved in growth regulation and inhibition.

WS6 is an inducer of β cell proliferation, thought to act primarily through modulating the activities of the IKB kinase pathway and ErbB3-binding protein 1 (EBP1). WS6 is also known to stimulate human ɑ cell proliferation. WS6 does not affect β cell differentiation, as no alteration in the number of insulin producing β cells is observed

特點和優勢

This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable