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Merck
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Key Documents

SML0370

Sigma-Aldrich

岩白菜素

≥98% (HPLC)

同義詞:

2-[(联苯-4-基)氨甲酰基] 苯甲酸, 4′-苯基邻苯二甲酸 (8CI), KGN

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About This Item

經驗公式(希爾表示法):
C20H15NO3
CAS號碼:
分子量::
317.34
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

溶解度

DMSO: >15 mg/mL

儲存溫度

room temp

SMILES 字串

O=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O

InChI

1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)

InChI 密鑰

SLUINPGXGFUMLL-UHFFFAOYSA-N

生化/生理作用

Kartogenin 诱导多能间充质干细胞 (MSCs) 选择性分化为软骨细胞。Kartogenin 与细丝蛋白 A 结合,破坏了细丝蛋白 A 和 CBFβ 之间的特异性相互作用(核心结合因子 β亚单位)。显然,kartogenin 通过调节 CBFβ 的核定位诱导软骨形成.
Kartogenin是小杂环化合物。它参与Runt相关转录因子1(RUNX1)的调节,在软骨细胞增殖和存活中起重要作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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