SAB5900404

Anti-Monkeypox virus/MPXV E8L Antibody (SAA0285)

• 同義詞: E8L, Cell surface-binding protein, Carbonic anhydrase homolog, Monkeypox virus (MPXV)
• 分類程式碼代碼: 12352203

屬性

• 生物源: mouse
• 品質等級: 100
• 重組細胞: expressed in CHO cells
• 共軛: unconjugated
• 抗體表格: affinity purified immunoglobulin
• 無性繁殖: SAA0285, recombinant monoclonal
• 化驗: >95% (SDS-PAGE)
• 形狀: liquid
• 分子量: 150 kDa
• 物種活性: monkeypox virus
• 濃度: 1 mg/mL
• 技術: ELISA: 1:2000-1:4000; neutralization: 0.01-10 μg/mL
• 顏色: colorless
• pH值: 7.4
• 同型: IgG2a, kappa
• Protein ID登錄號: NP_536532.1
• UniProt登錄號: Q8V4Y0
• 運輸包裝: wet ice
• 儲存溫度: -65 to -96°C
• 目標翻譯後修改: unmodified

描述

一般說明

Anti-Monkeypox virus/MPXV E8L Antibody, clone SAA0285, is a hybrid protein of mouse and human origin, consisting of a single light chain and a single heavy chain. The light chain is composed of a variable region (VL) and a constant region (CL) while the heavy chain is composed of a variable region (VH) and a constant region (CH). The VL and VH regions are responsible for the binding of the antibody to the antigens on the Monkeypox virus, while the CL and CH regions are responsible for the production of anti-viral proteins.
Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

特異性

Monoclonal Anti-Monkeypox virus/MPXV E8L Antibody, clone SAA0285 binds to the antigens on the surface of the Monkeypox virus, blocking the virus from entering host cells. It also activates the production of anti-viral proteins, which neutralize the virus and inhibit its replication. The antibody also activates the immune system, helping to clear the virus from the body.

應用

ELISA,neutralization

包裝

100µg per vial / 1 mg per vial

儲存和穩定性

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable