SAB5701486

Anti-PUMA antibody produced in rabbit

• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: monoclonal
• 形狀: liquid
• 物種活性: rat, human, mouse
• 濃度: 0.85 mg/mL
• 技術: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登錄號: Q96PG8/Q9BXH1
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BBC3(27113)

描述

一般說明

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

免疫原

A synthesized peptide derived from human PUMA

外觀

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable