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Merck
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重要文件

07-1406

Sigma-Aldrich

Anti-GLUT-5 Antibody, a.a. 490-502

serum, from rabbit

同義詞:

Fructose transporter, Glucose transporter type 5, small intestine, glucose transporter-like protein 5, solute carrier family 2 (facilitated glucose transporter),

member 5, solute carrier family 2 (facilitated glucose/fructose

transporte

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, guinea pig, mouse

技術

western blot: suitable

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Slc2A5(56485)

一般說明

A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels.

特異性

Recognizes GLUT-5.

免疫原

Epitope: C-terminus
Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse.

應用

Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

品質

Evaluated by Western Blot in Mouse kidney lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.

標靶描述

Approx. 54 kDa

聯結

Replaces: AB1348

外觀

Unpurified rabbit serum
Liquid containing 0.05% sodium azide.

儲存和穩定性

Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles.

分析報告

Control
Mouse kidney lysate.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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Irene Zwarts et al.
Scientific reports, 9(1), 9299-9299 (2019-06-28)
Fructose has become a major constituent of our modern diet and is implicated as an underlying cause in the development of metabolic diseases. The fructose transporter GLUT5 (SLC2A5) is required for intestinal fructose absorption. GLUT5 expression is induced in the
Ana Andres-Hernando et al.
Cell metabolism, 32(1), 117-127 (2020-06-06)
Intake of fructose-containing sugars is strongly associated with metabolic syndrome. Compared with other sugars, dietary fructose is uniquely metabolized by fructokinase. However, the tissue-specific role of fructokinase in sugar-induced metabolic syndrome, and the specific roles of glucose and fructose in

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