SAB5700359

Anti-Phospho-STAT6-Y641 antibody produced in rabbit

• 同義詞: D12S1644, IL-4-STAT, STAT6, STAT6B, STAT6C
• 分類程式碼代碼: 12352203
• NACRES: NA.43

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 74; 81; 94
• 物種活性: human
• 濃度: 1.42 mg/ml
• 技術: western blot: 1:500-1:2000
• UniProt登錄號: P42226
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr641)
• 基因資訊: human ... STAT6(6778)

描述

一般說明

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

免疫原

A phospho specific peptide corresponding to residues surrounding Y641 of human STAT6

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable