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Key Documents

SAB4502489

Sigma-Aldrich

Anti-Parathyroid Hormone antibody produced in rabbit

affinity isolated antibody

同義詞:

PTH/PTHr receptor, PTH/PTHrP type I receptor, PTHR1, Parathyroid hormone/parathyroid hormone-related peptide receptor precursor

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 12 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... PTH(5741)

一般說明

Anti-Parathyroid Hormone antibody detects endogenous levels of total parathyroid hormone protein.
The PTH (parathyroid hormone) gene is mapped to human chromosome 11p15.3.

免疫原

The antiserum was produced against synthesized peptide derived from human Parathyroid Hormone.

Immunogen Range: 51-100

生化/生理作用

PTH (parathyroid hormone) significantly maintains calcium and phosphate homeostasis. The function of PTH is brought about by PTH receptor, a G protein-coupled receptor. Upregulation of PTH is observed in hyperparathyroidism, which leads to hypertension, bone and cardiovascular disease. PTH is also known to improve fracture healing.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Parathyroid pathology: hyperparathyroidism and parathyroid tumors.
Carlson D
Archives of Pathology & Laboratory Medicine, 134(11), 1639-1644 (2010)
Effects of parathyroid hormone 1-34 on osteogenic and chondrogenic differentiation of human fracture haematoma-derived cells in vitro.
Dogaki Y
Journal of Tissue Engineering and Regenerative Medicine, 10(10), E365-E371 (2016)
Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport.
Sneddon WB
The Journal of Biological Chemistry, 291(36), 18632-18642 (2016)
Genetic Variants Associated with Circulating Parathyroid Hormone.
Robinson-Cohen C
Journal of the American Society of Nephrology, 28(5), 1553-1565 (2017)
N Demirkan et al.
International journal of immunopathology and pharmacology, 27(2), 253-260 (2014-07-10)
The aim of this study is to investigate the histopathological findings of drill hole healing and interactions of parathyroid hormone (PTH), β-catenin and transcription factor-4 (TCF7L2/Tcf-4) after local application of recombinant human bone morphogenic protein-2 (rhBMP-2). Sprague Dawley rats were

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