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Merck
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重要文件

05-517

Sigma-Aldrich

Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1

clone 3D1.1, Upstate®, from mouse

同義詞:

Anti-BDE2, Anti-HHM, Anti-PLP, Anti-PTHR, Anti-PTHRP

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

3D1.1, monoclonal

物種活性

pig, human, mouse

製造商／商標名

Upstate®

技術

immunohistochemistry: suitable
western blot: suitable

同型

IgG1κ

NCBI登錄號

NM_000315

UniProt登錄號

P12272

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... PTHLH(5744)

特異性

Recognizes PTH/PTHrP receptor and the receptor dimer.

免疫原

Synthetic peptide corresponding to amino acids 146-169 of the human PTH/PTHrP (parathyroid hormone/parathyroid hormone related protein) receptor (RRCDRNGSWELVPGHNRTWANYSE).

應用

Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1 is an antibody against PTH/PTHrP Receptor for use in IH & WB.
Research Category
Neuroscience
Research Sub Category
Hormones & Receptors

品質

Routinely evaluated by immunoblot on RIPA lysates of 3T3-L1 pre-adipose fibroblasts

標靶描述

80 kDa; receptor dimer at 160 kDa

外觀

Protein G Purified
Format: Purified
Protein G Purified immunoglobulin in Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

儲存和穩定性

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析報告

Control
Kidney Tissue

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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Christine V Marzan et al.
Developmental biology, 349(2), 125-136 (2010-10-27)
We generated a transgenic (Tg)-mouse model expressing a dominant negative-(DN)-RARα, (RARαG303E) under adipocytes-specific promoter to explore the paracrine role of adipocyte retinoic acid receptors (RARs) in mammary morphogenesis. Transgenic adipocytes had reduced level of RARα, β and γ, which coincided
Cell-specific effects of nitric oxide deficiency on parathyroid hormone-related peptide (PTHrP) responsiveness and PTH1 receptor expression in cardiovascular cells.
Rolf Schreckenberg, Sibylle Wenzel, Rui Manuel da Costa Rebelo, Anja Rothig, Rainer Meyer et al.
Endocrinology null
Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone.
Gao, J; Tiwari-Pandey, R; Samadfam, R; Yang, Y; Miao, D; Karaplis, AC; Sairam, MR; Goltzman, D
Endocrinology null
Nathalie Alekos et al.
JCI insight (2023-02-03)
The energetic costs of bone formation require osteoblasts to coordinate their activities with tissues, like adipose, that can supply energy-dense macronutrients. In the case of intermittent parathyroid hormone treatment (PTH), a strategy used to reduce fracture risk, bone formation is
Kimberly J Curtis et al.
Journal of the Royal Society, Interface, 17(173), 20200568-20200568 (2020-12-17)
Most patients who succumb to cancer have metastases to bone that contribute to their death. Cancer cells that metastasize to bone are regularly subjected to mechanical stimuli that may affect their proliferation, growth and protein expression. Understanding why some cancer
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