推薦產品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 34 kDa
物種活性
human, rat, mouse
濃度
~1 mg/mL
技術
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... FCGR2B(2213)
一般說明
The human immune system has six FcγRs-FcγRI, FcγRIIA, FcγRIIB, FcγRIIC, FcγRIIIA and FcγRIIIB. FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) is an inhibitory receptor that is located on human chromosome 1q23.
Anti-CD32 Antibody detects endogenous levels of total CD32 protein.
Anti-CD32 Antibody detects endogenous levels of total CD32 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human CD32.
Immunogen Range: 277-326
Immunogen Range: 277-326
生化/生理作用
FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) controls the generation of autoantibodies and their effector roles. During a viral memory response, FcγRIIB blocks the generation of inflammatory type I IFN from plasmacytoid dendritic cells.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Fc?RIIB prevents inflammatory type I IFN production from plasmacytoid dendritic cells during a viral memory response
Flores M, et al.
Journal of Immunology (2015)
Fc?RIIB and autoimmunity
Espeli M, et al.
Immunological Reviews (2016)
Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism Fc?RIIB-T232
Xu L, et al.
The Journal of Experimental Medicine (2016)
Association of a transmembrane polymorphism of Fcgamma receptor IIb (FCGR2B) with systemic lupus erythematosus in Taiwanese patients
Chen JY, et al.
Arthritis and Rheumatism (2006)
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