推薦產品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
predicted mol wt 133 kDa
物種活性
mouse, rat, human
濃度
1 mg/mL
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pSer1177)
基因資訊
human ... NOS3(4846)
免疫原
Peptide sequence around phosphorylation site of serine 1177 (T-Q-S(p)-F-S), according to the protein NOS3.
應用
Recommended dilutions
Western Blot 1:500 - 1:1000
Optimal dilutions should be determined by the user.
Western Blot 1:500 - 1:1000
Optimal dilutions should be determined by the user.
生化/生理作用
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Solution in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Chemico-biological interactions, 313, 108821-108821 (2019-09-17)
Decrease in the bioavailability of vasoactive nitric oxide (NO), derived from the endothelial nitric oxide synthase (NOS3), underlines vascular endothelial damage. Our expanding knowledge on mature red blood cells (RBCs) makes it supposable that RBCs might contribute to vascular function
Contribution of eNOS variants to the genetic susceptibility of coronary artery disease in a Tunisian population.
Genetic Testing and Molecular Biomarkers, 19, 203-208 (2015)
Hypertension research : official journal of the Japanese Society of Hypertension, 41(11), 923-931 (2018-09-07)
This study was designed to investigate the effects of uric acid on vascular endothelial function in measurements carried out either at the bedside or the laboratory bench. First, we performed reactive hyperemia peripheral arterial tonometry using an EndoPAT 2000 device
Post-Transcriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Polypyrimidine Tract-Binding Protein 1.
Arteriosclerosis, Thrombosis, and Vascular Biology, 35, 2153-2160 (2015)
Surfactant protein-D deficiency suppresses systemic inflammation and reduces atherosclerosis in ApoE knockout mice.
Cardiovascular Research, 113, 1208-1218 (2017)
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