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Key Documents

SAB4502013

Sigma-Aldrich

Anti-ENOS antibody produced in rabbit

affinity isolated antibody

同義詞:

Constitutive NOS, EC-NOS, ECNOS, Endothelial NOS, cNOS

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 133 kDa

物種活性

human, rat, mouse

濃度

~1 mg/mL

技術

ELISA: 1:40000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NOS3(4846)

一般說明

Anti-ENOS Antibody detects endogenous levels of total ENOS protein.
The ENOS (endothelial nitric oxide synthase) gene is mapped to human chromosome 7q36.1. ENOS is expressed predominantly in the endothelial cells.

免疫原

The antiserum was produced against synthesized peptide derived from human eNOS.

Immunogen Range: 581-630

應用

Anti-ENOS antibody produced in rabbit has been used in SDS-PAGE and western blotting.

生化/生理作用

ENOS (endothelial nitric oxide synthase) is responsible for the production of nitric oxide. eNOS is known to stimulate vasodilation and regulate inflammation and myocyte function. Impairment of endothelium-dependent vasodilatation that is observed in acute hyperglycaemia condition is due to suppression of ENOS. The gene might be involved in lipolysis. Variation in ENOS might lead to Henoch-Schönlein purpura. ENOS polymorphism affects the NO concentration in plasma.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

The role of the eNOS G894T and T-786C gene polymorphism in the development of ascites in cirrhosis.
Yildirim O
European Review for Medical and Pharmacological Sciences, 20(22), 4725-4730 (2016)
(-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: Potential role of endothelial nitric oxide synthase.
Ramirez-Sanchez I
Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease, 13(3), 201-210 (2016)
Mechanisms underlying the hypotensive and vasodilator effects of Ru(terpy)(bdq)NO](3+), a nitric oxide donor, differ between normotensive and spontaneously hypertensive rats.
Potje SR
European Journal of Pharmacology, 741, 222-229 (2014)
Association of Endothelial Nitric Oxide Synthase Gene Polymorphism with Susceptibility and Nephritis Development of Henoch-Schonlein Purpura in Chinese Han Children.
Wang A
Genetic Testing and Molecular Biomarkers, 21(6), 373-381 (2017)
Heat-shock protein 60 of Porphyromonas gingivalis may induce dysfunction of human umbilical endothelial cells via regulation of endothelial-nitric oxide synthase and vascular endothelial-cadherin.
Wu C
Biomedical Reports, 5(2), 243-247 (2016)

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