SAB1306484

ANTI-BECLIN 1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 同義詞: BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 51896 Da
• 物種活性: mouse, human
• 技術: flow cytometry: 1:10-1:50; immunohistochemistry: 1:50-1:100; western blot: 1:1000
• NCBI登錄號: NP_003757.1
• UniProt登錄號: Q14457
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BECN1(8678)

描述

一般說明

Beclin 1 (BECN1) or GT197 is a tumor suppressor gene. It is a 450 amino-acid protein having three domains. The gene encoding BECN1 is localized on human chromosome 17q21.

應用

ANTI-BECLIN 1 antibody produced in rabbit has been used for Western blotting.

生化／生理作用

Beclin 1 (BECN1) or GT197 acts as an initiator of autophagy and is vital in the early stages of autophagosome formation. It has a role in various tumors and cancers. BECN1 is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking.

外觀

Supplied in PBS with 0.09% (W/V) sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable