推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 67 kDa
物種活性
rat, mouse, human
濃度
~1 mg/mL
技術
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NFE2L2(4780)
一般說明
Nrf2 （核因子，红细胞2 相关因子2）基因位于人类染色体2q31.2。该编码蛋白位于树突状细胞。它属于转录因子的cap ′n′ collar (CNC) 家族。
抗-NRF2抗体检测内源性总NRF2蛋白水平。
免疫原
抗血清通过靶向来自人Nrf2的合成肽产生。
免疫原范围： 556-605
免疫原范围： 556-605
應用
兔中产生的抗-NRF2，C-末端抗体已被用于蛋白质印迹分析中。
生化／生理作用
Nrf2 （核因子，红细胞2 相关因子2）参与抗氧化和抗炎反应的调节。该编码蛋白是一种转录因子，与靶基因的抗氧化反应元件结合。出于对氧化应激的响应，Nrf2上调与解毒、抗炎、细胞保护和抗氧化通路相关的酶的水平。通过调节磷酸戊糖途径，Nrf2影响癌症细胞中的葡萄糖代谢和ROS（活性氧）稳态。因此，现已确知Nrf2通过促进细胞增殖促使癌症发生。
特點和優勢
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果，我们将给予您完全的赔偿或更换抗体。 了解更多。
外觀
兔IgG，溶于磷酸盐缓冲盐水（不含Mg2+和Ca2+），pH7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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