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Merck
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重要文件

S2067

Sigma-Aldrich

S9 from Liver, Pooled

from rat(Sprague-Dawley), male

同義詞:

Liver S9 Fraction, S9 Liver Extract

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About This Item

分類程式碼代碼:
12161501
NACRES:
NA.47

生物源

rat (Sprague-Dawley)

品質等級

包裝

vial of ~20 mg

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

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應用

S9 from Liver, Pooled has been used in metabolic activation in Salmonella typhimurium strains.

生化/生理作用

Post-mitochondrial supernatant fraction from homogenized liver. Source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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分析證明 (COA)

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Genotoxicity evaluation of locally produced dental porcelain-An in vitro study using the Ames and Comet assays
Noushad M, et al.
Toxicology in vitro, 23(6), 1145-1150 (2009)
The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 46(3), 169-172 (2001)
Milena Lopes Francisco Bittencourt et al.
Life sciences, 256, 117977-117977 (2020-07-01)
Silibinin is the major component of flavonolignans complex mixture (Silymarin), which is obtained from Silybum marianum (L.) Gaertn. Despite several reports about silibinin, little is known about its effects on gastric diseases. Then, the present study aims to evaluate the
Leonara Fayer et al.
Toxicology research, 10(3), 511-522 (2021-06-19)
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