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Merck
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重要文件

S2192

Sigma-Aldrich

S9 from Liver, Pooled

from mouse(CD-1), male, 20 mg/mL protein basis, vial of 1.0 mL

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About This Item

分類程式碼代碼:
12161501
NACRES:
NA.47

生物源

mouse (CD-1)

品質等級

包裝

vial of 1.0 mL

濃度

20 mg/mL protein

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

mouse ... Rps9(76846)

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生化/生理作用

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. They are known to be a rich source of drug metabolizing enzymes including P-450. S9 pools are useful in the study of xenobiotic metabolism and drug interactions. They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

外觀

Supplied as a solution in 150 mM KCl, 50 mM Tris buffer, pH 7.2 and 2 mM EDTA.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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分析證明 (COA)

Lot/Batch Number

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The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 46(3), 169-172 (2001)

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