RAB0166

磷酸化EGFR（pTyr¹⁰⁶⁸) 和pan-EGFR ELISA试剂盒

for detection of human phospho-egfr (pTyr¹⁰⁶⁸) and pan-egfr in cell and tissue lysates

• 分類程式碼代碼: 41116158
• NACRES: NA.32

屬性

• 物種活性: human
• 包裝: kit of 96 wells (12 strips x 8 wells)
• 技術: ELISA: suitable; capture ELISA: suitable
• 輸入: sample type: human cell lysate; sample type: human tissue lysate
• 檢測方法: colorimetric
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... EGFR(1965)

描述

一般說明

The Phospho-EGFR (pTyr¹⁰⁶⁸) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

免疫原

EGFR (pTyr¹⁰⁶⁸) synthetic phosphopeptide, Recombinant Human EGFR

應用

请参考Protocol了解详情。

生化／生理作用

EGFR (epidermal growth factor receptor) functions as a receptor for EGF-family of proteins, which are peptide growth factors. This receptor-ligand system is also involved in the pathogenesis and progression of various types of carcinomas. In cancer, EGFR pathways promotes cellular proliferation, angiogenesis, metastasis and apoptosis. The microRNA miR-218-5p interacts with and controls EGFR, and in non-small cell lung cancer (NSCLC), the levels of EGFR are inversely related to miR-218-5p. miR-218-5p inhibits proliferation and migration of lung cancer cells by binding with EGFR, and thus, has potential in future NSCLC therapies. Phospho-EGFR activates phospho-Akt pathway in invasive bladder cancer (BC) and it can be considered as a promising therapeutic target for cancer.

其他說明

Phosphorylated and pan protien can both be measured , in one experimnet.

安全資訊

• 象形圖: GHS05
• 訊號詞: Warning
• 危險聲明: H290
• 防範說明: P234 - P390
• 危險分類: Met. Corr. 1
• 儲存類別代碼: 8B - Non-combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable