PZ0151

PF-956980 hydrate

≥98% (HPLC)

• 同義詞: {(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-pyrrolidin-1-yl-methanone hydrate
• 經驗公式（希爾表示法）: C₁₈H₂₆N₆O · xH₂O
• CAS號碼: 1262750-62-8
• 分子量：: 342.44 (anhydrous basis)
• MDL號碼: MFCD18452852
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329823736
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +33 to +40°, c = 0.5 in methanol
• 顏色: white to off-white
• 溶解度: DMSO: ≥50 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: O.C[C@@H]1CCN(C[C@@H]1N(C)c2ncnc3[nH]ccc23)C(=O)N4CCCC4
• InChI: 1S/C18H26N6O.H2O/c1-13-6-10-24(18(25)23-8-3-4-9-23)11-15(13)22(2)17-14-5-7-19-16(14)20-12-21-17;/h5,7,12-13,15H,3-4,6,8-11H2,1-2H3,(H,19,20,21);1H2/t13-,15+;/m1./s1
• InChI 密鑰: VZUKSTKLTSSYKP-PBCQUBLHSA-N

描述

生化／生理作用

PF-956980 is a FGF1 receptor antagonist; PDGF receptor modulator; Flt3 tyrosine kinase modulator; and VEGF antagonist.

特點和優勢

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301 + H311 + H331
• 防範說明: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable