P9797

溴吡斯的明

• 同義詞: 3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide
• 經驗公式（希爾表示法）: C₉H₁₃BrN₂O₂
• CAS號碼: 101-26-8
• 分子量：: 261.12
• EC號碼: 202-929-9
• MDL號碼: MFCD00079283
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24277865
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 品質等級: 100
• 形狀: solid
• 溶解度: water: 100 mg/mL, clear to very slightly hazy, colorless
• 起源: Valeant
• SMILES 字串: [Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• InChI 密鑰: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• 基因資訊: human ... ACHE(43)

描述

應用

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

生化／生理作用

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

Acetylcholinesterase inhibitor.

特點和優勢

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H300 + H310 + H330 - H317
• 防範說明: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• 危險分類: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
• 儲存類別代碼: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges