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P5874

Sigma-Aldrich

PTACH

≥98% (HPLC), solid

同義詞:

Cpd 51, S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate

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About This Item

經驗公式(希爾表示法):
C20H26N2O2S2
CAS號碼:
分子量::
390.56
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

solid

溶解度

DMSO: 26 mg/mL

儲存溫度

2-8°C

SMILES 字串

CC(C)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c2ccccc2

InChI

1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)

InChI 密鑰

MDYDGUOQFUQOGE-UHFFFAOYSA-N

生化/生理作用

HDAC inhibitor; more potent than the majority of HDAC inhibitors except for SAHA (gold standard).

特點和優勢

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Minghui Wang et al.
Neuron, 109(2), 257-272 (2020-11-26)
To identify the molecular mechanisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics profiling of four cortical areas across 364 donors with varying cognitive and neuropathological phenotypes. Our analyses revealed thousands

文章

Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.

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