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Merck
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重要文件

P4630

Sigma-Aldrich

蛋白酶 来源于牛胰腺

Type I, ≥5 units/mg solid

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About This Item

CAS號碼:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
eCl@ss:
32160410
NACRES:
NA.54

生物源

bovine pancreas

品質等級

種類

Type I

形狀

powder

比活性

≥5 units/mg solid

儲存溫度

−20°C

相關類別

應用

蛋白酶是一种可通过水解肽键来分解蛋白质的酶。蛋白酶可用于降解蛋白质、研究蛋白酶抑制剂以及研究热灭活动力学。产品P4630来自牛胰腺。来自牛胰蛋白酶(I型)的蛋白酶已被用于提取半纤维素

生化/生理作用

蛋白酶可通过肽键的水解而使蛋白分解代谢。蛋白酶可被丝氨酸活性位点抑制剂所灭活,如苯甲基磺酰氟(PMSF)和二异丙基氟磷酸盐。

品質

粗品

單位定義

除特殊声明,在 pH 7.5,37 °C条件下下,一单位在每分钟内可水解酪蛋白以生成与1.0 μ摩尔(181 μg)酪氨酸相当的颜色(颜色来自Folin-Ciocalteu试剂)。

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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P A Hedin et al.
The Journal of nutrition, 124(12), 2458-2465 (1994-12-01)
The southwestern corn borer, Diatraea grandiosella Dyar, is a major pest of corn, Zea mays L., in the southern United States. To search for plant allelochemicals, chemically defined insect diets are commonly used, but southwestern corn borer larvae did not
Werend Boesmans et al.
Glia, 67(6), 1167-1178 (2019-02-08)
Coordination of gastrointestinal function relies on joint efforts of enteric neurons and glia, whose crosstalk is vital for the integration of their activity. To investigate the signaling mechanisms and to delineate the spatial aspects of enteric neuron-to-glia communication within enteric
Marc Machnik et al.
Drug testing and analysis, 9(9), 1372-1384 (2016-09-24)
Methylxanthines positives in competition samples have challenged doping control laboratories and racing jurisdictions since methylxanthines are naturally occurring prohibited substances and often constituents of feed. For theobromine, an international threshold (renamed in International Residue Limit, IRL) of 2 µg/mL in urine
Nir Qvit et al.
Pharmaceuticals (Basel, Switzerland), 15(3) (2022-03-27)
Myocardial infarction is the leading cause of cardiovascular mortality, with myocardial injury occurring during ischemia and subsequent reperfusion (IR). We previously showed that the inhibition of protein kinase C delta (δPKC) with a pan-inhibitor (δV1-1) mitigates myocardial injury and improves
U Klöckner
Pflugers Archiv : European journal of physiology, 424(3-4), 231-237 (1993-08-01)
Calcium-activated chloride currents were studied by the patch-clamp technique in vascular smooth muscle cells (VSMC) isolated from human mesenteric arteries. Bath application of 20 mM caffeine caused the cell membrane to depolarize by a calcium-activated inward current that peaked to

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To standardize a procedure for the enzymatic assay of Protease using Casein as a substrate.

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