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O7753

Sigma-Aldrich

草酰乙酸

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC)

同義詞:

2-氧代丁二酸, 丁酮二酸, 氧代丁二酸, 草醋酸

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About This Item

線性公式:
HOOCCH2COCOOH
CAS號碼:
分子量::
132.07
Beilstein:
1705475
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.75

生物源

synthetic (organic)

品質等級

產品線

BioReagent

化驗

≥97% (HPLC)

形狀

powder

技術

cell culture | insect: suitable
cell culture | mammalian: suitable

溶解度

H2O: 100 mg/mL

儲存溫度

−20°C

SMILES 字串

OC(=O)CC(=O)C(O)=O

InChI

1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)

InChI 密鑰

KHPXUQMNIQBQEV-UHFFFAOYSA-N

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一般說明

草酰乙酸是一种二羧酸,存在于人体的每个细胞中。它是三羧酸(TCA)循环和糖异生的代谢中间体。

應用

草酰乙酸已用于评价对肌萎缩性侧索硬化症(ALS)模型超氧化物歧化酶1 (SOD1) G93A小鼠神经肌肉功能和寿命的影响。它还被用作杜氏改良Eagles培养基(DMEM)的补充剂,用于培养鸡成纤维细胞(DF-1)和化学永生化来角雄性肝癌(LMH)细胞,以进行功能验证实验。

生化/生理作用

草酰乙酸在中枢代谢中起重要作用。它可抑制琥珀酸脱氢酶,是线粒体代谢的一种关键调节剂。

相關產品

產品號碼
描述
訂價

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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