N8652

NF 023 hydrate

≥98% (HPLC), solid

• 同義詞: 8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate
• 經驗公式（希爾表示法）: C₃₅H₂₀N₄O₂₁S₆ · 6Na · xH₂O
• CAS號碼: 104869-31-0
• 分子量：: 1162.88 (anhydrous basis)
• MDL號碼: MFCD11046019
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24278597
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• 顏色: white to off-white
• 溶解度: H₂O: >20 mg/mL
• SMILES 字串: O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O
• InChI: 1S/C35H26N4O21S6.6Na.H2O/c40-33(38-25-7-9-27(63(49,50)51)23-13-21(61(43,44)45)15-29(31(23)25)65(55,56)57)17-3-1-5-19(11-17)36-35(42)37-20-6-2-4-18(12-20)34(41)39-26-8-10-28(64(52,53)54)24-14-22(62(46,47)48)16-30(32(24)26)66(58,59)60;;;;;;;/h1-16H,(H,38,40)(H,39,41)(H2,36,37,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60);;;;;;;1H2/q;6*+1;/p-6
• InChI 密鑰: FLINBQMOKZJBEC-UHFFFAOYSA-H
• 基因資訊: human ... P2RX1(5023) , P2RY1(5028) , P2RY11(5032) , P2RY2(5029)

描述

應用

NF 023 hydrate has been used as an inhibitor of methyltransferases. It has also been used to test its inhibitory effect on human adenovirus type-37 (HAdV-D37) viral infection in human corneal epithelial (HCE) cells.

生化／生理作用

NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.

特點和優勢

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

包裝

Desiccate

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves