跳轉至內容
Merck
全部照片(1)

重要文件

N4382

Sigma-Aldrich

萘啶酸 钠盐

powder

同義詞:

1-乙基-1,4-二氢-7-甲基-4-氧代-1,8-萘啶-3-羧酸 钠盐

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C12H11N2NaO3
CAS號碼:
分子量::
254.22
Beilstein:
3580062
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.77

形狀

powder

品質等級

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

作用方式

DNA synthesis | interferes
enzyme | inhibits

起源

Sanofi Aventis

SMILES 字串

[Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12

InChI

1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1

InChI 密鑰

ROKRAUFZFDQWLE-UHFFFAOYSA-M

尋找類似的產品? 前往 產品比較指南

一般說明

化学结构:喹诺酮类
萘啶酸是一种喹诺酮,通过抑制细菌II型拓扑异构酶的活性,阻断细菌复制。相较革兰氏阳性菌,它对革兰氏阴性菌有较强抗菌作用。萘啶酸已用于尿道感染治疗研究。

應用

萘啶酸已用于处理细菌培养物,研究它对肠道沙门菌鼠伤寒沙门氏菌的抗性。

生化/生理作用

萘啶酸钠盐是细菌 DNA 聚合酶(DNA 旋转酶)和禽髓母细胞瘤病毒逆转录酶的抑制剂。在 酿酒酵母中抑制核酸和蛋白质合成。

特點和優勢

该化合物由Sanofi Aventis开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处
这种化合物是细胞凋亡研究的特色产品。点击此处发现更多特色细胞凋亡产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Carc. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

客戶也查看了

Crystal Y Chen et al.
PLoS pathogens, 5(4), e1000392-e1000392 (2009-04-22)
The role of CD8 T cells in anti-tuberculosis immunity in humans remains unknown, and studies of CD8 T cell-mediated protection against tuberculosis in mice have yielded controversial results. Unlike mice, humans and nonhuman primates share a number of important features
Margarita A Arreguin-Nava et al.
Animals : an open access journal from MDPI, 9(9) (2019-09-20)
The effect of Lactobacillus spp.-based probiotic candidates on Salmonella enterica serovar Enteritidis (SE) colonization was evaluated in two separate experiments. In each experiment, sixty-one day-of-hatch female turkey poults were obtained from a local hatchery. In both experiments, poults were challenged
Michelle H Larsen et al.
Vaccine, 27(34), 4709-4717 (2009-06-09)
Tuberculosis (TB) remains a global health burden for which safe vaccines are needed. BCG has limitations as a TB vaccine so we have focused on live attenuated Mycobacterium tuberculosis mutants as vaccine candidates. Prior to human studies, however, it is
Daniel Hernandez-Patlan et al.
Frontiers in veterinary science, 6, 108-108 (2019-05-21)
Decreases in the use of antibiotics and anticoccidials in the poultry industry have risen the appearance of necrotic enteritis (NE). The purpose of this study was to evaluate the effect of a Bacillus direct-fed microbial (DFM) on growth performance, intestinal
Arantxa Morales-Mena et al.
Animals : an open access journal from MDPI, 10(10) (2020-10-15)
This study's objective was to evaluate the effect of the fermented soybean meal (FSBM) on Salmonella typhimurium (ST) to turkey poults using two models of infection. In the prophylactic model, one-day-old turkeys were randomly allocated to one of four different

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務